45 Marksam Rd, Guelph resides in the area of the city of Guelph. , and the city of Ariss is also close by.

Nearby restaurants are few and far between. If you love coffee, you're not too far from Tim Hortons located at 232 Silvercreek Parkway N. Groceries can be found at Helal Freshmeat and Supermarket which is only a 3 minute walk and you'll find Food Basics Pharmacy only an 8 minute walk as well. As for close-by schools, St Peter Separate School and Wellington Catholic District School Board are a 5-minute walk from 45 Marksam Rd, Guelph.

Getting around the area will require a vehicle, as there are no nearby transit stops.